Cats use the connection governing parallel transport in the space of shapes to land safely on their feet. Here we argue that this connection also explains the impressive performance of molecular motors by enabling molecules to evade conclusions of Feynman’s ratchet-and-pawl analysis. We first demonstrate, using simple molecular models, how directed rotational motion can emerge from shape changes even without angular momentum. We then computationally design knotted polyalanine molecules and show how their shape space connection organizes individual atom thermal vibrations into collective rotational motion, independently of angular momentum. Our simulations show that rotational motion arises effortlessly even in ambient water, making the molecule an effective theory time crystal. Our findings have potential for practical molecular motor design and engineering and can be verified through high-precision nuclear magnetic resonance measurements.
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